Advanced Technology Core Facilities

A thin slice of frozen brain tissue from the hippocampus of a cloned pig

Advanced Light Microscopy

120 Bond Life Sciences Center / 573-882-4895 / Director: Tara Finegan

Equipment and services consist of confocal, super-resolution, digital light-sheet and widefield microscopes, laser capture micro dissection, image analysis and processing and sample preparation. Facility statement.

image of zygote superimposed onto image of a mouse

Animal Modeling

4011 Discovery Drive, Room S121 / 573-884-1804 / Co-Directors: Director: Elizabeth Bryda and Daniel Davis

Provides a variety of essential services associated with the generation, characterization and maintenance of animal models for both internal and external clients. Facility statement.

Image of data from A new paper including Drs Coghill and Raju from the BAC as co-authors looks at a multi-Omic approach to exploring the role for MCT2 in the host response to TC1 lung carcinoma that involve alterations in the gut and systemic metabolome, along with TAM-related metabolic pathway.

Bioinformatics and Analytics

106 Bond Life Sciences Center / 573-882-3026 / Director: Hong An (interim)

Provides informatics support services, develops tools and leverages high-performance computing resources for the UM System and its universities and their researchers. Facility statement.

Image of the MO-Flo laser

Cell & Immunobiology

M324 Medical Sciences Building / 573-884-7315 / Director: Susan Rottinghaus

The CIC is comprised of two facilities. The Tissue Culture Facility offers essential services, including maintenance and preparation of normal and tumor cells for in vitro and in vivo experiments, training and LN storage services. The Supply Center offers convenience and cost-savings on many lab products, including plasticware, cell, protein and flow items. Facility statement.
This core is managed by the MU School of Medicine.

Brain

Cognitive Neuroscience Systems

15 Melvin H. Marx Building / 573-882-4785 / Director: Brett Froeliger

Providing state-of-art instrumentation and laboratory space for conducting translational cognitive neuroscience research. Facility statement.

Image of NextGen Precision Health building and created image of tiger head

Electron Microscopy

0011 NextGen Precision Health Building / 573-884-5383 / Director: Min Su

Provides electron microscopy services and technology to investigators from academia and industry. The core offers access to scanning and transmission electron microscopes, as well as ancillary equipment and services. Facility statement.

Sample readings on rainbow background

Flow Cytometry

2408D NextGen Precision Health building / 573-882-3833 / Director: Yue Guan

Flow cytometry is a powerful technology for analyzing and sorting a suspension of microscopic particles at thousands of events per second. The technique utilizes fluorescent probes targeted to cell-specific antigens to characterize the physical and/or chemical characteristics of single cells.

Proteomics results

Gehrke Proteomics Center

214 Bond Life Sciences Center / 573-884-7374 / Director: Brian Mooney

The center provides advanced technologies in protein separation and mass spectrometry identification for researchers. Facility statement.

Image from Genomics Technology Core

Genomics Technology

216 Bond Life Sciences Center / 573-882-0428 / Director: Nathan Bivens and Assistant Director Grant Zane

Provides genomic services to UM System investigators, external academic researchers and commercial entities. The core is a resource to educate and train researchers / students in the use of sequencing technologies. Facility statement.

LIDR building

Laboratory for Infectious Disease Research

1020 East Campus Loop / 573-884-3808 / Director: Anthony Griffiths

The mission of the Laboratory for Infectious Disease Research is to provide state-of-the-art facilities to support research on infectious diseases. The Laboratory includes the Aerobiology Core, Immunology Core, Microbiology Core and Animal Infection and Monitoring Services (AIMS) Core. Facility statement.

Panorama of lab

Metabolomics Center

243 Bond Life Sciences Center / 573-882-5596 / Director: Lloyd W. Sumner and Assistant Director Zhentian Lei

The mission of the University of Missouri Metabolomics Center (MUMC) is to provide advanced, cutting-edge metabolomics capabilities and expertise to both the MU community and outside entities. Facility statement.

Rigaku XtaLAB SuperNova

Molecular Interactions

125 Bond Life Sciences Center / 573-882-9024 / Director: Kamal Singh

The mission of the Molecular Interactions Core (formerly Structural Biology Core) is to enhance the research infrastructure available to MU life scientists by ensuring sustained access to functional state-of-the-art equipment and expertise in the fields of structural biology, molecular interactions and peptide synthesis. Facility statement.

Images from testing

Nuclear Magnetic Resonance Core

125 Chemistry Building / 573-884-7807 / Director: Michael Greenlief

The mission of the Nuclear Magnetic Resonance Facility is to enhance the research infrastructure available to MU scientists by ensuring access to state-of-the-art instrumentation for the structural elucidation of molecules by NMR spectroscopy. Facility statement.
This core is managed by the MU College of Arts & Science.

Dog in MRI

PET Imaging Center

900 E. Campus Drive / 573-882-7821 / Director: Jeffrey Bryan

Housed in the College of Veterinary Medicine, the PET/CT Imaging Core is a crucial component and important tool in the effort to embrace science at the intersection of humans, animals and the ecosystem. The Core includes a combination positron tomography (PET) scanner and computed tomography (CT) – the PET/CT system – which improves accuracy and speed in the diagnosis and treatment of cancer, vascular disorders and Lou Gehrig’s disease, among others. Facility statement.

Ernie and Lotte Sears Plant Growth Facility

Plant Transformation

Sears Plant Growth Facility / 573-882-7705 / Director: Bing Yang

The goal of the Plant Transformation Core at the University of Missouri is to enhance both basic and applied research in plant biology by providing fee-based plant transformation services. Facility statement.
This core is managed by the MU College of Agriculture, Food and Natural Resources.

Visualsonics Vevo 2100 output

Small Animal Phenotyping

C102A, Dalton Cardiovascular Research Center / 573-882-9482 / Director: Kevin Cummings (interim)

Providing for in vivo study of cardiovascular function, metabolism, drug distribution and aspects of behavior and learning. Facility statement.

Collage of equipment

X-ray Microanalysis

Room 1 Geological Sciences Building / 573-882-9501 / Director: James D. Schiffbauer

At the X-ray Microanalysis Core (MizzoµX), we not only explore electron- and X-ray microscopy techniques on fossil materials, but also have built a broad group of collaborators outside of paleontology and geological sciences to apply these techniques to expansive specimen types. We are happy to provide free consultation to best plan and assess your analytical needs, and will work with you to provide full service through the completion of your project. Facility statement.
This core is managed by the MU College of Arts & Science.