The Molecular Interactions Core (MIC) offers assistance in unraveling the three-dimensional structure of biological molecules as well as biomolecular substrate and ligand interactions. The MIC also provides custom peptides and peptidomimetics for researchers from MU and national and international institutes.
The MIC offers technical expertise in biomolecular interaction, protein purification and crystallization, peptide synthesis, nanodisc assembly and computer-aided drug design. The MIC supports instrumentation for X-ray diffraction, protein/protein and protein/ligand interaction, protein/nucleic secondary structure determination, particle size determination. The peptide synthesis capabilities includes PNA conjugates, combinatorial peptide libraries, labeled peptides and peptidomimetics. The MIC also offers Custom HPLC-MS analytical and preparative purification services.
To get started, contact us or learn more about the services below:
- Dynamic Light Scattering
- Peptide Synthesis
- Custom LC-MS
New x-ray system
We recently installed a Rigaku XtaLAB SuperNova, which includes a high-flux, low maintenance microfocus sealed tube. The system is a compact, yet full-featured and is the ideal diffractometer for crystallography research laboratories.
New peptide synthesizer
Our Peptide Synthesis Core includes a new Advanced ChemTech Tetras Peptide Synthesizer. The new synthesizer is capable of performing independent peptide synthesis with variable scales, activations, lengths, and sequences.