The Laboratory for Infectious Disease Research’s Animal Infection and Monitoring Services (AIMS) core is led by Dr. Rachel Olson, Chief Scientific Officer of the Laboratory for Infectious Disease Research (LIDR). AIMS can support work on agents up to BSL-3 in a variety of animal models and routes of infection and access to up-to-date instrumentation.
The LIDR animal facility is AALAC accredited, with 2,478 square feet of updated ABSL-3 space in two independent suites, each with two housing rooms and a dedicated procedure room. The holding rooms at LIDR are suitable for animals from small rodents up to small livestock.
AIMS offers one-on-one consultations, animal model development and refinement services, study support, sample processing and analysis and support for grant and manuscript preparation.
Services
Model Development/Model Refinement
AIMS offers consultation services to aid in the selection of the proper animal model and infection route given investigator’s study goals and limitations.
Study Support
AIMS extends study support for challenges with human-relevant pathogens up to BSL-3. We offer necropsy support, in vivo imaging, post challenge health monitoring and more.
Sample Processing and Analysis
AIMS offers analysis for antibody responses, blood chemistry values, cytokines, cytotoxicity and histopathology.
Reporting and Communication
AIMS coordinates with the LIDR Aerobiology, Immunology and Microbiology cores to ensure a wide range of access to resources. Additionally, AIMS offers pre- and post-study support for grant and manuscript preparation.
Getting Started
For investigators new to LIDR
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Contact Dr. Rachel Olson.
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Additional training is required for independent use of the LIDR vivarium or AIMS equipment.
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Due to CDC and USDA regulations, only individuals who have undergone an FBI Security Risk Assessment (SRA) and meet ongoing suitability and personnel reliability requirements are permitted to work independently in any LIDR BSL-3 or ABSL-3 spaces.
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All work requiring an escort will have a $41.50/hour fee assessed, as well as incur charges for the cost of entry.
For returning investigators
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Fill out and submit the AIMS Project Intake Form.
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Contact Dr. Rachel Olson with questions.
Instruments
Features
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25mm field of view, providing next level scalability
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Nikon FX-format camera for high-speed, high-sensitivity imaging
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Low-signal, multi-channel fluorescence imaging
For more information, please read the product brochure.
Scheduling
Contact Chris Johanning to schedule training or use.
Rates, Forms and Guidelines
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Prices effective September 1, 2023
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Rates are per hour and tracked to the nearest 15-minute increment
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All operators must be trained before independent use is allowed
For more information on fees and who to contact, please review the AIMS Fee Information document.
| Service | Internal academic investigator | External academic investigator | Commercial investigator |
|---|---|---|---|
| Training, hourly | $41.50 | $60 | $150 |
| Hourly, independent use | $40 | N/A | N/A |
| Hourly, with facility operator | $81.50 | $120 | $200 |
Acknowledgement
All work performed in our facility should be properly acknowledged in published manuscripts, presentations, posters and press releases. This acknowledgement provides a visible measure of the core's impact and is essential for our continued funding.
Features
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Capable of 12-color Fluorescence and 12-color bright field studies
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Cell counting for live, dead, and apoptotic cells
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Integrated software suites for real time data visualization
For more information, please read the product brochure.
Scheduling
Contact Chris Johanning to schedule training or use.
Rates, Forms and Guidelines
-
Prices effective September 1, 2023
-
Rates are per hour and tracked to the nearest 15-minute increment or per unit, as applicable
-
All operators must be trained before independent use is allowed
For more information on fees and who to contact, please review the AIMS Fee Information document.
| Service | Internal academic investigator | External academic investigator | Commercial investigator |
|---|---|---|---|
| Training, hourly | $41.50 | $60 | $150 |
| Per plate | $125 | $175 | $225 |
Acknowledgement
All work performed in our facility should be properly acknowledged in published manuscripts, presentations, posters and press releases. This acknowledgement provides a visible measure of the core's impact and is essential for our continued funding.
Features
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Flow based, multiplex assays
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1300+ kits available on the Luminex website
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Cloud-based data analysis with Thermo Fisher ConnectTM
For more information, please read the product brochure.
Scheduling
Contact Chris Johanning to schedule training or use.
Rates, Forms and Guidelines
-
Prices effective September 1, 2023
-
Rates are per hour and tracked to the nearest 15-minute increment or per unit, as applicable
-
All operators must be trained before independent use is allowed
For more information on fees and who to contact, please review the AIMS Fee Information document.
| Service | Internal academic investigator | External academic investigator | Commercial investigator |
|---|---|---|---|
| Training, hourly | $41.50 | $60 | $150 |
| Up to 96 well plate* | $130 | $205 | $250 |
| Up to 384 well plate* | $171.50 | $210 | $255 |
*Assay provided by investigator. Assay may be performed by AIMS personnel at the hourly training rate.
Acknowledgement
All work performed in our facility should be properly acknowledged in published manuscripts, presentations, posters and press releases. This acknowledgement provides a visible measure of the core's impact and is essential for our continued funding.
All studies conducted with the LagoX are currently operator supported. LagoX support services are overseen by Dr. Olson.
The LagoX has a large field-of-view that accommodates up to 10 mice simultaneously, and can follow small animal disease model progression, responses to therapeutics and cell migration in vivo.
Features
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High-speed, digital bioluminescence, fluorescence and x-ray imaging
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High-throughput; 10 mice at once
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14 fluorescent excitation wavelengths, 20 fluorescent emission filters
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Integrated software for rapid visualization
For more information, please read the LagoX brochure.
Scheduling
Contact Chris Johanning to schedule training or use.
Rates, Forms and Guidelines
-
Prices effective September 1, 2023
-
Rates are per hour and tracked to the nearest 15-minute increment
-
All operators must be trained before independent use is allowed
For more information on fees and who to contact, please review the AIMS Fee Information document.
| Service | Internal academic investigator | External academic investigator | Commercial investigator |
|---|---|---|---|
| Training, hourly | $41.50 | $60 | $100 |
| x-ray use w/facility operator | $90 | $115 | $165 |
| BLI/FLI use w/facility operator | $115 | $140 | $190 |
Acknowledgement
All work performed in our facility should be properly acknowledged in published manuscripts, presentations, posters and press releases. This acknowledgement provides a visible measure of the core's impact and is essential for our continued funding.
Features
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High-speed, high-throughput ECL
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No liquid consumables, lower cost of use
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Wide selection of assay kits, with support for user designed assays on the MesoScale website
For more information, please read the product brochure.
Scheduling
Contact Chris Johanning to schedule training or use.
Rates, Forms and Guidelines
-
Prices effective September 1, 2023
-
Rates are per hour and tracked to the nearest 15-minute increment or per unit, as applicable
-
All operators must be trained before independent use is allowed
For more information on fees and who to contact, please review the AIMS Fee Information document.
| Service | Internal academic investigator | External academic investigator | Commercial investigator |
|---|---|---|---|
| Training, hourly | $40 | $60 | $100 |
| Per plate | $125 | $200 | $275 |
Acknowledgement
All work performed in our facility should be properly acknowledged in published manuscripts, presentations, posters and press releases. This acknowledgement provides a visible measure of the core's impact and is essential for our continued funding.
Features
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High-speed, high-throughput chemistry analyzer; up to 75 samples per run
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Flexible analysis allows for running a single assay or complex custom panels
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Vet Axcel Test Menu (PDF)
Scheduling
Contact Chris Johanning to schedule training or use.
Rates, Forms and Guidelines
-
Prices effective September 1, 2023
-
Rates are per hour and tracked to the nearest 15-minute increment
For more information on fees and who to contact, please review the AIMS Fee Information document.
| Service | Internal academic investigator | External academic investigator | Commercial investigator |
|---|---|---|---|
| Operation, hourly | $41.50 | $60 | $100 |
| Use, per specimen* | $0.50 | $1.50 | $4 |
*Assays are charged per specimen. Assay kits are an additional cost and are not included in the cost of operation.
Acknowledgement
All work performed in our facility should be properly acknowledged in published manuscripts, presentations, posters and press releases. This acknowledgement provides a visible measure of the core's impact and is essential for our continued funding.