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Bruker timsTOF-PRO

Bruker timsTOF Pro

  • Hybrid trapped ion-mobility spectrometry, quadrupole, time-of-flight LC-MS+MS/MS
  • Accurate mass, high resolution, instrument (routinely <10 parts per million, 50,000 resolution)
  • High-coverage global quantitative proteomics
  • PTM mapping and quantitation

 

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ThermoFisher Scientific LTQ Orbitrap XL

ThermoFisher Scientific LTQ Orbitrap XL

  • Hybrid ion trap, Orbitrap mass spectrometer
  • Accurate mass instrument (routinely < 5 ppm on precursor)
  • High resolution, typically 30,000 for peptides
  • Very high resolution possible (>100,000 at m/z 400)
  • Reversed-phase separation of peptides using integrated Proxeon nano-HPLC

 

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Agilent 6520 Accurate Mass QTOF

Agilent 6520 Accurate Mass QTOF

  • Hybrid quadrupole time-of-flight mass spectrometer
  • Integrated nano-HPLC
  • Integrated CHIP CUBE (microfluidic C18 column for peptide separation)
  • Typical peptide resolution >10,000
  • Typical peptide mass accuracy <5 ppm

 

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Amersham IPGphor & Bio-Rad Protean IEF

Amersham IPGphor & Bio-Rad Protean IEF

  • Isoelectric focusing units

 

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Amersham SE 600, Ettan DALTsix and SE62

Amersham SE 600, Ettan DALTsix, & SE62

  • Second-dimension gel electrophoresis and electrophoretic transfer units

 

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Fujifilm FLA5000

Fujifilm FLA5000

  • Laser imaging system (three lasers, dual photomultiplier tubes)
  • Capable of imaging Cy2, Cy3, Cy5 dyes, Sypro, ProQ, etc. fluorescent stains
  • Phosphoimaging capability (NO radioactive samples are allowed in the Center)

 

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Waters Xevo TQ-S

Waters Xevo TQ-S

  • Triple quadrupole mass spectrometer
  • UHPLC with ESI or APCI source
  • High sensitivity and quantitation of targeted compounds in both positive and negative ion modes
  • Part of the Small Molecule MS Lab