The Directed Analysis MS Lab provides liquid chromatography/mass spectrometry service in support of quantitative analysis by MS.
The Lab has a Xevo Absolute triple quadrupole mass spectrometer with associated UPLC system on which all analyses are performed. The current focus is on targeted quantitative analysis, i.e., in which the client provides a standard for each analyte of interest.
Current and future users should note: before planning use of the Lab's facilities for research, analyses or before applying for grants, please consult with us about your requirements and time needs. This will permit us to best match your goals with available methods.
Instrument Access Rates
(available to on-campus users only)
| Instrument | Time block | Rate (self-service) | Rate (assisted) |
|---|---|---|---|
| Xevo/UPLC | per hour | $36 | $46 |
| Xevo/UPLC | half day (6 hours) | $163 | $229 |
| Xevo/UPLC | day (8 hour min) | $229 | $306 |
| Xevo/UPLC | week | $1121 | $1630 |
Scheduling
Access the Xevo Schedule.
User Education
The following presentations were given during the 2013 Life Sciences Week Metabolomics Workshop and are made available here as pdfs. The presenters have asked that none of their slides or data be included in any other presentation without their express permission.
- "Mass Spectrometry 101 and Beyond", Steve Slahck (Waters Corp.)
- "Practical Application of UPLC-MS/MS for Targeted Metabolite Analysis", Abe Koo (MU Department of Biochemistry)
- "Metabolomics, a Useful Technique for Functional Genomics and Systems Biology", Mingjie Chen (Thelen Lab, MU Department of Biochemistry)