The University of Missouri IRB may charge fees for certain studies to cover the costs associated with the IRB's review and related administrative responsibilities. 

Effective April 1, 2022

Contact our office about IRB fees prior to April 1, 2022.

Fees when MU is the IRB of Record

Single Site Study1,2

DescriptionFee
New Study Application$2,500
Annual Renewal$1,500

 

1MU must be engaged in the research.

2Waived for single site federal, state, nonprofit and not-for-profit sponsors and MU departmentally funded studies with no external contract/sponsoring entity. Fee applies to private, for profit and industry sponsors.

Multi-Site Study sIRB Review3

DescriptionProtocol Review Fees4Relying Site Fees5,6
Initial Review$2,500$1,200 to $3,000
Per Year Fees (includes annual update and 2 amendments)$2,500$1,200 to $3,000
Additional Fees for multiple site-level amendments $500

 

3MU IRB will only serve as the IRB of record for studies where the University is engaged in the research. MU IRB will not serve as the IRB of record for international sites.

4For federally-funded studies, Protocol Review Fees are waived since MU will be a participating site and these fees are covered as part of the indirect costs associated with Facilities and Administration (F&A) rate.

5Consultation required with MU IRB prior to any external sites being added to a new or existing study. Not all sites will meet the criteria necessary to participate and the number of sites allowed will be determined based upon study specific criteria. Fees charged for relying sites include secondary activities which may include negotiating reliance agreements, communicating with the sites about IRB oversight, reviewing site and investigator qualifications, collecting site-specific information, revising and issuing site-specific consent forms, evaluating adverse events and other site-specific updates, and reviewing site-specific information at the time of continuing review. These fees will be dependent upon the study design and site specifics and should be included by the lead site (MU) in the grant budget as direct costs.

6Relying site must have Federalwide Assurance (FWA). MOU required if relying site does not have an IRB.

 

Fees when MU is not the IRB of Record

Reliance Study1,2

DescriptionFee

Administrative one-time review fee

Any fees charged by an independent IRB are the responsibility of the lead site.

$1,500

 

1MU must be engaged in the research.

2Waived for single site federal, state, nonprofit and not-for-profit sponsors and MU departmentally funded studies with no external contract/sponsoring entity. Fee applies to private, for profit and industry sponsors.

 

Additional notes on fees

  • The actual costs of the review are still incurred if
    • subjects are never enrolled,
    • the study closes before milestones are met,
    • expenditures exceed revenue,
    • or a contract is never finalized.
  • When the IRB decides to table or disapprove a research protocol, no additional fee will be charged for reconsideration.
  • We ask that you include these fees as a line item in the budget of the formal contract as an upfront and non-refundable item.

 

Contact the Human Subjects Research office

310 Jesse Hall
Email: muresearchirb@missouri.edu Phone: 573-882-3181 Fax: 844-341-6544

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