The University of Missouri IRB charges fees to cover the costs associated with the IRB's review and related administrative responsibilities.
Effective April 1, 2022
Contact our office about IRB fees prior to April 1, 2022.
Fees when MU is the IRB of Record1,2
Single Site Study
|New Study Application||$2,500|
Multi-Site Study sIRB Review3
|Description||Protocol Review Fees4||Relying Site Fees5,6|
|Initial Review||$2,500||$1,200 to $3,000|
|Per Year Fees (includes annual update and 2 amendments)||$2,500||$1,200 to $3,000|
|Additional Fees for multiple site-level amendments||$500|
Fees when MU is not the IRB of Record1,2
Administrative one-time review fee
Any fees charged by an independent IRB are the responsibility of the lead site.
- MU must be engaged in the research.
- Waived for single site federal, state, nonprofit, and not-for-profit sponsors and MU departmentally funded studies with no external contract/sponsoring entity. Fee applies to private, for profit and industry sponsors.
- MU IRB will only serve as the IRB of record for studies where the University is engaged in the research. MU IRB will not serve as the IRB of record for international sites.
- For federally-funded studies, Protocol Review Fees are waived since MU will be a participating site and these fees are covered as part of the indirect costs associated with Facilities and Administration (F&A) rate.
- Consultation required with MU IRB prior to any external sites being added to a new or existing study. Not all sites will meet the criteria necessary to participate and the number of sites allowed will be determined based upon study specific criteria. Fees charged for relying sites include secondary activities which may include negotiating reliance agreements, communicating with the sites about IRB oversight, reviewing site and investigator qualifications, collecting site-specific information, revising and issuing site-specific consent forms, evaluating adverse events and other site-specific updates, and reviewing site-specific information at the time of continuing review. These fees will be dependent upon the study design and site specifics and should be included by the lead site (MU) in the grant budget as direct costs.
- Relying site must have Federalwide Assurance (FWA). MOU required if relying site does not have an IRB.
Notes on fees charged
- The actual costs of the review are still incurred if
- subjects are never enrolled,
- the study closes before milestones are met,
- expenditures exceed revenue,
- or a contract is never finalized.
- When the IRB decides to table or disapprove a research protocol, no additional fee will be charged for reconsideration.
- We ask that you include these fees as a line item in the budget of the formal contract as an upfront and non-refundable item.