Updated Aug. 14, 2026
University of Missouri researchers who conduct studies with human participants complete training modules through the Collaborative Institutional Training Initiative (CITI Program), and starting Aug. 31, the Division of Research is requiring additional one-time training modules. View IRB training webpage.
Mizzou's Human Subjects Research Protections Program (HRPP) provides oversight for Institutional Review Board (IRB) policies and procedures that protect the welfare of research participants. New required and optional training modules are being introduced to:
- Enhance the quality and completeness of IRB submissions.
- Streamline the review process by reducing the number of submissions returned for revisions.
- Ensure awareness of regulatory and institutional requirements.
- Increase awareness of study coordinating responsibilities.
One-time trainings required as of Aug. 31
Basic training
- New, non-student researchers must complete this training module in addition to CITI training modules.
- This module covers the basic components of the IRB application and requirements, in addition to the ethical standards embedded within IRB policies and covered by federally required CITI training.
Principal Investigators (PI) Responsibilities Training
- All new, non-student PIs were required to complete this training module as of May 18. Starting Aug. 31, the requirement extends to PIs on Amendment Forms and the Reliance Reporting Form (when MU is relying on an external IRB).
- The goal is to ensure PIs, who are ultimately responsible for all activities occurring throughout a study, are well-prepared for key oversight responsibilities.
Coordinating Responsibilities Training
- Individuals submitting any type of study on behalf of a PI must complete this training module, including those on Amendment Forms and the Reliance Reporting Form (when MU is relying on an external IRB).
- Co-Investigators submitting on behalf of a PI may be able to substitute PI Responsibilities training to meet this requirement depending on previous PI experience.
- Those who completed this module for a clinical study in May do not have to repeat the training.
- The goal is to ensure individuals submitting information to the IRB are well-prepared and have discussed key components of the IRB application with the PI and other study team members before submission.
Student IRB Training
- Student researchers must complete this training, a requirement that took effect in August 2024.
Optional training and handouts
Mizzou's HRPP/IRB team also has developed downloadable handouts and new optional modules that provide more in-depth training in the following areas:
- Amendments — to prepare researchers for the types of questions and documents required for proposed changes to a study design.
- Noncompliance and Unanticipated Problems — to ensure researchers have access to noncompliance scenarios and are aware of how to report noncompliance to the IRB.
- Relying on External IRB — to ensure investigators relying on external IRBs for multisite research are prepared for the documents and processes that will be required by the MU IRB as a relying site.
Stay tuned for more optional trainings. Please email muresearchirb@missouri.edu to request specific topics.
Resources
How to access trainings
Log into eCompliance and select the Institutional Review Board tile.

Under prerequisites, click on "MU HRPP/IRB Training Modules."
