Conflict of Interest

The PHS Regulation

NIH Reminds Investigators to Disclose All Financial Interests.
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The 2011 revised PHS regulations:

In response to increased public scrutiny and concern about conflicts of interest at research Institutions, the Public Health Service (PHS) has redrafted its conflict of interest regulations (42 CFR Part 50 Subpart F, 45 C.F.R. Part 94). This increased public scrutiny is a result of both the increase in relationships between researchers and industry and the increased rate at which research is brought from the bench to the market place. Strengthening the existing regulation on managing financial conflicts of interest is key to assuring the public that the institutions PHS supports are taking a rigorous approach to managing the essential relationship between the government, federally funded research institutions, and the private sector. These revised regulations were effective August 24, 2012.

Who is covered by this regulation?

The regulation is applicable to each institution that applies for grants or cooperative agreements for research or submits a proposal for a research contract and all Investigators participating in that research with any of the following offices/agencies:

Other organizations may elect to adopt the PHS regulations or similar conflict of interest regulations. Some other sponsors that have conflict disclosure requirements are, but are not limited to:

What are the responsibilities of investigators under the PHS regulation?

PHS Investigators must disclose as directed under the policy of their institution. The revised PHS regulations are applicable to all Investigators who will participate in research funded under PHS grants or cooperative agreements.

Will disclosures be publically available?

Consistent with the PHS regulations, for senior/key personnel only, the University of Missouri must ensure public accessibility of interests which are identified as a Financial Conflict of Interest (FCOI) by the Conflict of Interest Committee. An FCOI exists when the Committee determines that an Investigator’s financial interest is related to a PHS-funded research project and could directly and significantly affect the design, conduct or reporting of the PHS-funded research. The public must submit a written request to the University of Missouri System Custodian of Records before the information will be released. The University will respond to written requests within five business days. The Conflict of Interest Office will notify Investigators of any requests that involve their disclosure so they will know when and to whom that information was given.

Where can I find additional information?

The National Institutes of Health (NIH) has compiled answers to the most frequently asked questions regarding the implementation of the revised regulations for grants and cooperative agreements. The questions are arranged by topic and can be found on NIH’s website.