Office of Grant Writing & Publications.

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) - Obstetric Pharmacology Research Units (U10) Network

Office of Grant Writing & Publications

202 Jesse Hall
University of Missouri
Columbia, MO 65211

573 882-9500 phone
573 884-8371 fax

Limited Submission Announcement

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) invites applications to participate in the Obstetric Pharmacology Research Units (U10) Network to serve as a resource for performance of pharmacologic studies of drug disposition and effect during normal and abnormal pregnancies. Within the Network, the OPRUs will: (1) conduct multi-site cooperative clinical studies of therapeutic modalities used during pregnancy; (2) conduct studies of fetal, placental and maternal pharmacology; (3) conduct studies on the effect of pregnancy on drug metabolizing enzymes, transporters and effectors, including interactions with pharmacogenetics/pharmacogenomics; (4) facilitate the collection and utilization of clinical materials for basic research studies; and (5) perform studies of placental metabolism and transfer of drugs; (6) enhance the exchange of information between basic scientists and obstetricians and among various specialists involved in treating pregnant women; (7) promote collaborations in interdisciplinary translational research. The Network will also serve as a resource for the training of health professionals, including pre- and post-doctoral fellows and PharmDs, in obstetric pharmacology, pharmacogenomics and clinical trials in pregnant women.

Because MU is limited to one application for this program, letters of intent must be submitted to the Office of Research,, no later than 4:00 p.m., Friday, January 30, 2009. Letters of intent should be limited to 3 pages and should include brief descriptions of plans for 1) the pharmacological component, 2) clinical studies, and 3) multidisciplinary, interactive basic and/or non-clinical research component.


This Funding Opportunity Announcement (FOA) will utilize the Cooperative Agreement (U10) grant mechanism. An applicant may request a project period of up to five years and a base budget for direct costs up to $650,000 per year.

MU Deadline:

4:00 p.m., Friday, January 30, 2009

Sponsor Deadlines:

March 30, 2009

URL for more information:

This notice is being sent to deans, directors, and chairs in health and life science disciplines. Please forward it to other faculty members who may be interested.

All limited submission announcements can be tracked by deadline via the Calendar at or by announcement date via the Limited Submissions listing at