Office of Grant Writing & Publications.

NIA Consortium for Clinical Trials on Anemia in Older Persons (U01)

Office of Grant Writing & Publications

202 Jesse Hall
University of Missouri
Columbia, MO 65211

573 882-9500 phone
573 884-8371 fax

Limited Submission Announcement

The National Institute on Aging (NIA) invites applications for a consortium to facilitate clinical trials on anemia in older persons consistent with the recommendations of the NIA Advisory Panel. During the six-year support period, the awardee will develop protocols and study procedures and implement several phase II clinical trials on effects of interventions against anemia or low normal hemoglobin levels on hematologic, clinical, and functional outcomes in older persons.

It is expected that studies with different protocols will run concurrently at a given clinical site. The topics of these protocols will be decided and prioritized cooperatively by the Consortium Steering Committee and implemented after review and approval by the Data and Safety Monitoring Board (DSMB) and NIA. Awardees can also develop and implement pilot translational and exploratory studies informing designs of the future trials. The first year of the award will provide funds to structure consortium operations and finalize protocol, data collection forms, and manual of procedures for the first trial.

The consortium will be funded as a cooperative agreement consisting of a coordinating center, at least three clinical sites, and the NIA. Applicants should propose other structural components (e.g., central laboratory) for the consortium. Applicants are encouraged to include personnel with expertise in the wide range of scientific areas pertinent to this research including hematology, geriatrics, biostatistics, clinical trials design and implementation, data management, central laboratory procedures, psychology, functional assessment methodology, and others.

Because MU is limited to one application for this program, letters of intent must be submitted to the Office of Research, ltdsub@missouri.edu, no later than 4:00 p.m. Friday, June 20, 2008. Letters of intent should be limited to a 3-page summary, including 1) proposed structure of the consortium, including anticipated faculty collaborators, 2) proposed research plan(s) and/or agenda(s) for the phase II intervention study, and 3) how the presence of this center will advance scientific knowledge on campus.

Amount:

The NIA intends to commit $800,000 in total costs (direct plus indirect) in fiscal year 2009 and $3 million per year in total costs (direct plus indirect) in fiscal years 2010 through 2014 to fund one six-year award.

MU Deadline:

4:00 p.m., Friday, June 20, 2008

Sponsor Deadline:

A non-required letter of intent is due October 7, 2008

Full proposals are due November 7, 2008.

URL for more information: http://grants1.nih.gov/grants/guide/rfa-files/RFA-AG-09-003.html

This notice is being sent to deans, directors, and chairs in the health sciences. Please forward it to faculty members who may be interested.

All limited submission announcements can be tracked by deadline via the Calendar at research.missouri.edu or by announcement date via the Limited Submissions listing at http://research.missouri.edu/ogwp/lsa.htm.