Office of Grant Writing & Publications.

NIH Biomarkers for Older Controls at Risk for Dementia (BIOCARD) Study Extension (U01)

Office of Grant Writing & Publications

202 Jesse Hall
University of Missouri
Columbia, MO 65211

573 882-9500 phone
573 884-8371 fax

Limited Submission Announcement

The National Institute on Aging (NIA) and National Institute of Mental Health (NIMH) solicit cooperative agreement applications that will provide for the medical, clinical, neuropsychological, and neuropsychiatric follow-up of individuals who were enrolled in the BIOCARD Study and to diagnose any participants who progress to mild cognitive impairment (MCI) or dementia, particularly Alzheimer's disease (AD). All of the previous clinical and neuropsychological data which have been collected, the biological samples which have been stored (plasma, CSF), and the MRI data from consenting participants will be provided to the successful grantee with the provision that a system will be set up to share these data and samples with the greater scientific community as well as the data and samples that will be collected during this extension period.

Applicants to this FOA are not permitted to submit a resubmission application, nor are renewal applications permitted.

Because MU is limited to one application for this program, letters of intent must be submitted to the Office of Research,, no later than 4:00 pm Friday, April 25, 2008. Letters of intent should be limited to a 3-page summary of the proposed project, including 1) an overview of proposed activities; 2) proposed medical, clinical, neuropsychological, and neuropsychiatric evaluations and the follow-up intervals (probably at least yearly) to assess progression to cognitive decline, MCI, and AD; 3) anticipated site for testing participants; and 4) plans for the consent process.


Up to $1.5 million in direct costs per year for a project period of up to five years

MU Deadline:

4:00 p.m., Friday, April 25, 2008

Sponsor Deadlines:

A non-required letter of intent is due May 11, 2008. Full proposals are due June 11, 2008

URL for more information:

This notice is being sent to deans, directors, and chairs in engineering, behavioral and life sciences. Please forward it to faculty members who may be interested.

All limited submission announcements can be tracked by deadline via the Calendar at or by announcement date via the Limited Submissions listing at