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Limited Submission Announcements

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The National Institutes of Health solicits U01 cooperative agreement applications that will set up an international network of scientific investigators that will have the responsibility to identify, recruit, evaluate, and follow-up individuals from families with early onset dominantly inherited Alzheimer's disease (i.e., families with the amyloid precursor protein (APP), presenilin 1 (PS1), and presenilin 2 (PS2) mutations or duplications or others still to be discovered). Applicants should propose a research design for a network that will allow collection and coordination of data on individuals from affected families. The aim of the network is to facilitate use of the data generated from these families in order to provide key information on understanding the initiation and progression of early onset dominantly inherited Alzheimer's disease.

Because MU is limited to one application for this program, letters of intent must be submitted to the Office of Research,, no later than 4:00 pm Friday, August 31, 2007. Letters of intent should include a 3-page summary of the proposed network, including overviews of the 1) coordinating center, 2) core facilities, 3) clinical sites, and 4) evaluations and procedures planned for subjects.


The NIA intends to commit approximately $2,200,000 in direct costs, with total costs up to $3,000,000 dollars in FY 2008 to fund one application. The total project period may not exceed 6 years.

MU Deadline:

4:00 p.m., Friday, August 31, 2007

Sponsor Deadline:

Non-required letters of intent are due by September 19, 2007.

The deadline for submission of applications is October 19, 2007.

URL for more information:

This notice is being sent to deans, directors, and chairs in life and health science disciplines. Please forward it to other faculty members who may be interested.

All limited submission announcements can be tracked by deadline via the Calendar at or by announcement date via the Limited Submissions listing at

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