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Limited Submission Announcements

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The NICHD is inviting applications from investigators willing to participate under a cooperative agreement in the Global Network for Women’s and Children’s Health Research, an ongoing multicenter international research network designed to perform randomized clinical trials of interventions to reduce the major risks to maternal, neonatal, infant, and early childhood health in the resource-poor countries. The purpose of this solicitation is to complement the existing Global Network with the addition of Research Units from Africa and India. The objective of this program is to contribute to the resolution of maternal and pediatric health problems by establishing a network of Research Units (paired U.S.-based and foreign centers) that will use common protocols to implement randomized clinical trials and thus contribute to the evidence base for sound clinical, programmatic, and policy decisions. The network will establish the infrastructure necessary to initiate, implement, and evaluate randomized controlled trials in community settings and health care facilities among pregnant women, newborns, infants, and children to the age of three years.

The overall goal of the Network is to expand scientific knowledge relevant to improving health outcomes for women and children in developing countries. Other critical goals are to develop sustainable research infrastructure and public health intervention capabilities in developing countries and to strengthen international collaborative research arrangements that focus on the leading causes of morbidity and mortality in pregnancy and early childhood. A key objective for the network Research Units is to design, develop, and conduct multiple simultaneous common clinical trials, as well as to evaluate and implement evidence-based health interventions and pertinent formative and translational research studies collaboratively. These studies must have a strong scientific and epidemiologic basis for their use in a foreign country, and should be culturally appropriate. The primary endpoints in these studies must be associated with demonstrable improvement in important public health measures in the population under study. This network will bring the required numbers of subjects into rigorously designed common protocols and thus address pressing research questions in pregnant women and very young children more quickly and efficiently than could individual centers acting alone.

Because MU is limited to one application for this program, letters of intent must be submitted to the Office of Research,, no later than 4:00 pm Friday, June 15, 2007. Letters of intent should be limited to three pages and should include a summary of the proposed project.


Project period of up to five years and a budget for direct costs up to $150,000 per year

MU Deadline:

4:00 p.m., Friday, June 15, 2007

Sponsor Deadline:

Letters of intent (optional) due June 26, 2007
Full proposal due July 27, 2007

URL for more information:

This notice is being sent to deans, directors, and chairs in health science disciplines. Please forward it to other faculty members who may be interested.

All limited submission announcements can be tracked by deadline via the Calendar at or by announcement date via the Limited Submissions listing at

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