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Limited Submission Announcements

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The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites applications for George M. O'Brien Kidney Research Core Centers to support both basic and clinical research on kidney disease. Core Centers should provide shared institutional and national resources to facilitate basic and clinical research on kidney disease and improve the effectiveness of translating insights from basic biology to clinical practice. The centers will also support pilot and feasibility studies to develop and test innovative approaches to therapy.

Much progress has been made since the initial solicitation for O'Brien Kidney Research Centers in 1987. The NIDDK is now further enhancing this program to allow for regional, national and even international collaboration. Until the past year, there had been a steady increase in the number of kidney disease patients progressing to end-stage disease. While there is still no cure for chronic kidney disease, the number of patients progressing to kidney failure now appears to be stabilizing, (possibly even decreasing). Despite this trend in the overall population, however, the same downturn in disease incidence has not been realized in minority populations, therefore many challenges remain in determining the genetic and pathophysiologic mechanisms of kidney disease that could potentially be targeted for therapeutic interventions.

Because MU is limited to one application for this program, letters of intent must be submitted to the Office of Research,, no later than 5:00 pm Friday, October 6, 2006. Letters of intent should be limited to three pages and should include a summary of the proposed center and the resources it would provide.


May request a project period of up to five years and direct costs of up to $150,000 per year.

MU Deadline: 5:00 p.m., Friday, October 6, 2006 (letter of intent)
Sponsor Deadline:

Friday, October 6 (letter of intent, optional)
November 21, 2006 (full proposal)

URL for more information:

This notice is being sent to deans, directors, and chairs in life science disciplines. Please forward it to other faculty members who may be interested.

All limited submission announcements can be tracked by deadline via the Calendar at or by announcement date via the Limited Submissions listing at

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