Office of Grant Writing & Publications.

NICHD Developmental Mechanisms of Human Structural Birth Defects (P01)

Office of Grant Writing & Publications

202 Jesse Hall
University of Missouri
Columbia, MO 65211

573 882-9500 phone
573 884-8371 fax

Limited Submission Announcement

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) invites applications for the Developmental Mechanisms of Human Structural Birth Defects (P01) program. This Funding Opportunity Announcement (FOA) solicits innovative, multidisciplinary, interactive, and synergistic program project (P01) grant applications from institutes and organizations that propose to integrate basic, translational, and clinical approaches to understanding the developmental biology and genetic basis of congenital structural human malformations.

To contain costs, each P01 will consist of only three component projects and associated cores. At least one project must use basic research in an animal model system and at least one project must be clinical or translational in nature. The component projects must share a common central theme, focus, or objective on a specific developmental structural malformation or class of anomalies that is genotypically, mechanistically, biologically, or phenotypically analogous or homologous in both animal models and humans.

Because MU is limited to one application for this program, letters of intent must be submitted to the Office of Research,, no later than 4:00 p.m. on Friday, September 17, 2010. Letters of intent should be limited to three pages and should include 1) the research focus and goals of the program, 2) a summary of the basic research project(s), 3) a summary of the translational/clinical component project(s), 4) a description of anticipated scientific cores, and 4) the names of three MU personnel who would be qualified to serve as internal reviewers for letters of intent under this program.


Up to $900,000 per year, exclusive of F&A costs on consortium/subcontract agreements, for a total project period of up to five years.

Campus Deadline for Letter of Intent:

4:00 p.m., Friday, September 17, 2010

External Proposal Deadlines:

Requested letters of intent are due October 30, 2010
Full proposals are due November 30, 2010


URL for more information:

All limited submission announcements can be tracked by deadline via the Calendar at or by announcement date via the Limited Submissions listing at