Office of Grant Writing & Publications.

NIAID Genomics of Transplantation Cooperative Research Program (U01, U19)

Office of Grant Writing & Publications

202 Jesse Hall
University of Missouri
Columbia, MO 65211

573 882-9500 phone
573 884-8371 fax

Limited Submission Announcement

The National Institute of Allergy and Infectious Diseases (NIAID) invites new or renewal applications from single institutions or consortia of institutions to participate in a cooperative interdisciplinary research program for large-scale, broad-scope genomic studies in clinical transplantation of solid organ, tissue, and cells.

The Genomics of Transplantation Cooperative Research Program (U01, U19) will support collaborative multidisciplinary teams with expertise in transplantation medicine, genetics, immunology, molecular biology, pharmacogenomics, biostatistics, and bioinformatics. The program goals are to identify and characterize gene polymorphisms and gene expression patterns that (1) correlate with and/or predict transplantation outcomes; (2) define immune responses relating to the onset and severity of acute and chronic graft rejection; (3) predict responses to immuno-suppression to allow tailoring of therapy; and (4) elucidate the genetic basis of variability in graft survival between populations or individuals. The long-term goal of the program is to understand the genetic basis of immune-mediated graft rejection and differences in transplant outcomes to provide a rational basis for developing more effective treatments to improve long-term graft survival and provide a better quality-of-life for transplant patients.

Because MU is limited to two applications for this program, letters of intent must be submitted to the Office of Research,, no later than 4:00 p.m. on Friday, September 10, 2010. Letters of intent should be limited to three pages and should include 1) the research focus and goals of the program, 2) a summary of the research plan(s), 3) a description of scientific cores, if proposed, and 4) the names of three MU personnel who would be qualified to serve as internal reviewers for letters of intent under this program.


The total project period may not exceed five years. Budgets for direct costs of up to $350,000 and $1.1 million per year for U01 and U19 applications, respectively, may be requested.

Campus Deadline for Letter of Intent:

4:00 p.m., Friday, September 10, 2010

External Proposal Deadlines:

Requested letters of intent are due October 19, 2010
Full proposals are due November 19, 2010


URL for more information:

All limited submission announcements can be tracked by deadline via the Calendar at or by announcement date via the Limited Submissions listing at