Office of Grant Writing & Publications.

NIEHS Engineered Nanomaterials: Linking Physical and Chemical Properties to Biology (U19)

Office of Grant Writing & Publications

202 Jesse Hall
University of Missouri
Columbia, MO 65211

573 882-9500 phone
573 884-8371 fax

Limited Submission Announcement

The National Institute of Environmental Health Sciences invites applications for the Engineered Nanomaterials: Linking Physical and Chemical Properties to Biology (U19) program. NIEHS is looking for projects that will (1) determine which physical or chemical characteristic of an engineered nanomaterial (ENM), or cluster of characteristics, is integral to ENM-molecular interactions in a cellular process or organ system and (2) relate these findings to potential health effects. NIEHS recognizes that three types of activities need to converge to accomplish this research agenda. The first activity should focus on a detailed understanding of how physical and chemical characteristics of ENMs influence their molecular interactions at the cellular level, while the second activity should determine how the physical and chemical characteristics critical to that interaction are associated with any observed physiological or pathobiological events. The third activity will capitalize on these multidisciplinary efforts through integration of biochemical, molecular, and physiological mechanisms to expand traditional hazard identification and health risk assessment. An extraordinary level of synergy, integration, and potential for advancement of ENM hazard identification and risk assessment is expected.

Because MU is limited to one application per school within the institution for this program, letters of intent must be submitted to the Office of Research,, no later than 4:00 p.m. on Wednesday, December 30, 2009. Letters of intent need only state key members involved with the project, their departments, and the school under which the proposal will be submitted. Due to the very short external deadline, interested parties are urged to proceed with proposal preparations. An internal review is not expected, only a coordination of efforts.


An applicant may request a project period of up to 5 years and a budget for direct costs up to $750,000 dollars per year.

MU Deadline:

4:00 p.m., Friday, December 30, 2009

Sponsor Deadlines:

January 22, 2010


URL for more information:

All limited submission announcements can be tracked by deadline via the Calendar at or by announcement date via the Limited Submissions listing at