Research Report '04
 MU Office of Research Home page. Year In Review. Technology Development. Sponsored Research. Instruction & Public Service. 2003 & Beyond.

Annual Report 2004 Query Tool

Investigators Continue on Path to 'Higher Level of Excellence'

Long Strands in Small Packages

New Insights Into an Old Reaction

Developed for Dogs, New 'Tissue Scaffolds' Offer Hope for Hobbled Humans

Deaton Named MU Chancellor

Gifts Revitalize Red Campus Research

Student Scholars Gain Smart New Space

Five MU Faculty Named AAAS Fellows

Expenditures and Awards

Developed for Dogs, New 'Tissue Scaffolds' Offer Home for Hobbled Humans

James Cook, an MU professor of veterinary medicine and surgery, is working with DePuy Orthopaedics, a Warsaw, Ind., based subsidiary of the Johnson & Johnson company, to perfect the use of surgically implanted "tissue scaffolds" to regrow the meniscus in damaged knees. The technique, which was recently approved for human clinical trials, promises to both repair knees and minimize the osteoarthritis that often follows surgery. "Other studies have shown the amount of arthritis a person experiences is related to the amount of meniscus they have left in the knee," Cook says. "In our animal studies, we have been able to grow back 90 percent of the meniscus on average. With approval from the federal government, we will now be able to begin using this in humans in the first phase of clinical trials."

While the new process has been used in more than 300 dogs, about 20 human patients will receive the procedure in the trials, which will be completed by surgeons in Memphis and Indianapolis. Following a successful first phase, the trials will be opened nationwide for a second, larger trial before finally being available to the public. Cook expects that process to take about 3-6 years.

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